Prothrombin Complex Concentrates Market Size, Growth Trends, Future Demand & Forecast 2028 | Octapharma AG, Nihon Pharmaceutical Co. Ltd., Grifols S.A., CSL Behring GmbH, Kedrion Biopharma Inc., Shire Plc, China Biologic Products Holdings, Inc., and Sanquin

Prothrombin Complex Concentrates

      Prothrombin Complex Concentrates




Factor lX complex, commonly known as prothrombin complex concentrate (PCC), is a medicine that contains the blood clotting factors ll, lX, and X. Factor Vll is also present in some versions. When pure factor lX is unavailable, it is used to treat and prevent haemophilia B bleeding. It can also be utilised in those who don't have enough of these components owing to other causes like warfarin treatment. It is injected into the body via a vein with a needle or syringe. Allergic reactions, vomiting, headaches, and tiredness are all common adverse effects. It can also cause dangerous adverse effects including blood clots, which can lead to heart attacks, strokes, and pulmonary embolism, among other things.


With it's therapeutic benefit over fresh frozen plasma, prothrombin complex concentrate (PCC) is expected to see a significant increase (FPP). In comparison to FPP, PCC needs less volume and time to infuse and is more effective. Like FPP, PCC does not need blood matching or thawing. These benefits of PCC make it preferable to FPP, increasing PCC's market demand. PCC has also benefited from recent government rules and policies, which have resulted in some relaxation in its usage permission.


Market segmentation:

By Product Type
  • 3-factor PCC
  • 4-factor PCC

By Application
  • Acquired Coagulation Factor Deficiency
  • Congenital Coagulation Factor Deficiency

By End User
  • Hospital & Ambulatory Surgical Centers
  • Specialty Clinics
  • Others

The market is expected to grow as anticoagulants, particularly warfarin, are prescribed more often and the frequency of bleeding disorders rises. PCC has a number of advantages over fresh-frozen plasma and other alternatives, making it perfect for life-threatening conditions. There were 68,703,141 I.U. in all. The Federation of World Hemophilia says so. In Europe, plasma-derived factor IX was utilised in 2020. As a result of the increased use of the factor IX complex, this market is expected to develop throughout the projected period.


The major key players operating in the global prothrombin complex concentrates market include Octapharma AG, Nihon Pharmaceutical Co. Ltd., Grifols S.A., CSL Behring GmbH, Kedrion Biopharma Inc., Shire Plc, China Biologic Products Holdings, Inc., and Sanquin

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